2015

List of publications

  • Ory B, Baud'huin M, Verrecchia F, Brounais-Le Royer B, Quillard T, Amiaud J, Battaglia S, Heymann D, Redini F, Lamoureux F. Blocking HSP90 addiction inhibits tumor cell proliferation, metastasis development and synergistically acts with zoledronic acid to delay osteosarcoma progression. Clin Cancer Res. 2015 Dec 28. - (MNT team: INSERM UMR 957 - Nantes)
  • Bigot N, Mouche A, Preti M, Loisel S, Renoud ML, Le Guével R, Sensebé L, Tarte K, Pedeux R. Hypoxia Differentially Modulates the Genomic Stability of Clinical-Grade ADSCs and BM-MSCs in Long-Term Culture. Stem Cells. 2015 Dec;33(12):3608-20. (MNT Team: INSERM UMR 917 – Rennes)
  • Redini F, Heymann D. Bone Tumor Environment as a Potential Therapeutic Target in Ewing Sarcoma. Front Oncol. 2015 Dec 23;5:279. - (MNT team: INSERM UMR 957 - Nantes)
  • Litwin M, Radwańska A, Paprocka M, Kieda C, Dobosz T, Witkiewicz W, Baczyńska D. The role of FGF2 in migration and tubulogenesis of endothelial progenitor cells in relation to pro-angiogenic growth factor production. Mol Cell Biochem. 2015 Dec;410(1-2):131-42. - (MNT Team: CNRS UPR4301 - CBM - Orléans)
  • Myszczyszyn A, Czarnecka AM, Matak D, Szymanski L, Lian F, Kornakiewicz A, Bartnik E, Kukwa W, Kieda C, Szczylik C. The Role of Hypoxia and Cancer Stem Cells in Renal Cell Carcinoma Pathogenesis. Stem Cell Rev. 2015 Dec;11(6):919-43. - (MNT Team: CNRS UPR4301 - CBM - Orléans)
  • Tertil M, Golda S, Skrzypek K, Florczyk U, Weglarczyk K, Kotlinowski J, Maleszewska M, Czauderna S, Pichon C, Kieda C, Jozkowicz A, Dulak J. Nrf2-heme oxygenase-1 axis in mucoepidermoid carcinoma of the lung: Antitumoral effects associated with down-regulation of matrix metalloproteinases. Free Radic Biol Med. 2015 Dec;89:147-57. - (MNT Team: CNRS UPR4301 - CBM - Orléans)
  • Ségaliny AI, Brion R, Brulin B, Maillasson M, Charrier C, Téletchéa S, Heymann D. IL-34 and M-CSF form a novel heteromeric cytokine and regulate the M-CSF receptor activation and localization. Cytokine. 2015 Dec;76(2):170-81. - (MNT team: INSERM UMR 957 - Nantes)
  • Noman MZ, Hasmim M, Messai Y, Terry S, Kieda C, Janji B, Chouaib S. Hypoxia: a key player in antitumor immune response. A Review in the Theme: Cellular Responses to Hypoxia. Am J Physiol Cell Physiol. 2015 Nov 1;309(9):C569-79. - (MNT Team: CNRS UPR4301 - CBM - Orléans)
  • Caron G, Hussein M, Kulis M, Delaloy C, Chatonnet F, Pignarre A, Avner S, Lemarié M, Mahé EA, Verdaguer-Dot N, Queirós AC, Tarte K, Martín-Subero JI, Salbert G, Fest T. Cell-Cycle-Dependent Reconfiguration of the DNA Methylome during Terminal Differentiation of Human B Cells into Plasma Cells. Cell Rep. 2015 Nov 3;13(5):1059-71. (MNT Team: INSERM UMR 917 – Rennes)
  • Deau E, Robin E, Voinea R, Percina N, Satała G, Finaru AL, Chartier A, Tamagnan G, Alagille D, Bojarski AJ, Morisset-Lopez S, Suzenet F, Guillaumet G. Rational Design, Pharmacomodulation, and Synthesis of Dual 5-Hydroxytryptamine 7 (5-HT7)/5-Hydroxytryptamine 2A (5-HT2A) Receptor Antagonists and Evaluation by [(18)F]-PET Imaging in a Primate Brain. J Med Chem. 2015 Oct 22;58(20):8066-96. - (MNT Team: CNRS UPR4301 - CBM - Orléans)
  • Amin R, Mourcin F, Uhel F, Pangault C, Ruminy P, Dupré L, Guirriec M, Marchand T, Fest T, Lamy T, Tarte K. DC-SIGN-expressing macrophages trigger activation of mannosylated IgM B-cell receptor in follicular lymphoma.Blood. 2015 Oct 15;126(16):1911-20. (MNT Team: INSERM UMR 917 – Rennes)
  • Szade K, Zukowska M, Szade A, Collet G, Kloska D, Kieda C, Jozkowicz A, Dulak J. Spheroid-plug model as a tool to study tumor development, angiogenesis, and heterogeneity in vivo. Tumour Biol. 2015 Sep 18. - (MNT Team: CNRS UPR4301 - CBM - Orléans)
  • Kervoëlen C, Ménoret E, Gomez-Bougie P, Bataille R, Godon C, Marionneau-Lambot S, Moreau P,Pellat-Deceunynck C, Amiot M. Dexamethasone-induced cell death is restricted to specific molecular subgroups of multiple myeloma.Oncotarget. 2015 Sep 29;6(29):26922-34.-(MNT Team: INSERM UMR 892/CNRS 6299 team 10 – Nantes)
  • Vacher P, Vacher AM, Pineau R, Latour S, Soubeyran I, Pangault C, Tarte K, Soubeyran P, Ducret T, Bresson-Bepoldin L. Localized Store-Operated Calcium Influx Represses CD95-Dependent Apoptotic Effects of Rituximab in Non-Hodgkin B Lymphomas. J Immunol. 2015 Sep 1;195(5):2207-15.(MNT Team: INSERM UMR 917 – Rennes)
  • Sousa S, Brion R, Lintunens M, Kronqvist P, Sandholm J, Mökkönen J, Kellokupu-Lehtinen PL, Tynninen O, Joensuu H, Heymann D, Määttä J. Human breast cancer cells educate macrophages toward the M2 activation status. Breast Cancer Res. 2015 Aug 5;17(1):101. - (MNT team: INSERM UMR 957 - Nantes)
  • Brennan M, Renaud A, Gamblin A, D’Arros C, Nedellec S, Trichet V, Layrolle P. 3D cell culture and osteogenic differentiation of human bone marrow stromal cells plated onto jet-sprayed or electrospun micro-fiber scaffolds. Biomedical Materials, 2015 Aug 4;10(4):045019. - (MNT team: INSERM UMR 957 - Nantes)
  • Mahévas M, Michel M, Vingert B, Moroch J, Boutboul D, Audia S, Cagnard N, Ripa J, Menard C, Tarte K, Mégret J, Le Gallou S, Patin P, Thai L, Galicier L, Bonnotte B, Godeau B, Noizat-Pirenne F, Weill JC, Reynaud CA. Emergence of long-lived autoreactive plasma cells in the spleen of primary warm auto-immune hemolytic anemia patients treated with rituximab. J Autoimmun. 2015 Aug;62:22-30. (MNT Team: INSERM UMR 917 – Rennes)
  • Ségaliny AI, Mohamadi A, Dizier B, Lokajczyk A, Brion R, Lanel R, Amiaud J, Charrier C, Boisson-Vidal C, Heymann D. Interleukin-34 promotes tumor progression and metastatic process in osteosarcoma through induction of angiogenesis and macrophage recruitment. Int J Cancer. 2015 Jul 1;137(1):73-85. - (MNT team: INSERM UMR 957 - Nantes)
  • Lamora A, Mullard M, Amiaud J, Brion R, Heymann D, Redini F, Verrecchia F. Anticancer activity of halofuginone in a preclinical model of osteosarcoma: inhibition of tumor growth and lung metastases. Oncotarget. 2015 Jun 10;6(16):14413-27. - (MNT team: INSERM UMR 957 - Nantes)
  • Grégoire M, Guilloton F, Pangault C, Mourcin F, Sok P, Latour M, Amé-Thomas P, Flecher E, Fest T, Tarte K. Neutrophils trigger a NF-κB dependent polarization of tumor-supportive stromal cells in germinal center B-cell lymphomas. Oncotarget. 2015 Jun 30;6(18):16471-87.(MNT Team: INSERM UMR 917 – Rennes)
  • Segaliny AI, Brion R, Mortier E, Maillasson M, Cherel M, Jacques Y, Le Goff B, Heymann D. Syndecan-1 regulates the biological activities of interleukin-34. Biochim Biophys Acta. 2015 May;1853(5):1010-21. - (MNT team: INSERM UMR 957 - Nantes)
  • Bustany S, Cahu J, Descamps G, Pellat-Deceunynck C, Sola B. Heat shock factor 1 is a potent therapeutic target for enhancing the efficacy of treatments for multiple myeloma with adverse prognosis. J Hematol Oncol. 2015 Apr 23;8:40.-(MNT Team: INSERM UMR 892/CNRS 6299 team 10 – Nantes)
  • Chiron D, Dousset C, Brosseau C, Touzeau C, Maïga S, Pellat-Deceunynck C, Le Gouill S, Amiot M. Biological rational for sequential targeting of Bruton tyrosine kinase and Bcl-2 to overcome CD40-induced ABT-199 resistance in mantle cell lymphoma. Oncotarget. 2015 Apr 20;6(11):8750-9.-(MNT Team: INSERM UMR 892/CNRS 6299 team 10 – Nantes)
  • Amé-Thomas P, Hoeller S, Artchounin C, Misiak J, Braza MS, Jean R, Le Priol J, Monvoisin C, Martin N, Gaulard P, Tarte K. CD10 delineates a subset of human IL-4 producing follicular helper T cells involved in the survival of follicular lymphoma B cells.Blood. 2015 Apr 9;125(15):2381-5. (MNT Team: INSERM UMR 917 – Rennes)
  • Maïga S, Brosseau C, Descamps G, Dousset C, Gomez-Bougie P, Chiron D, Ménoret E, Kervoelen C, Vié H, Cesbron A, Moreau-Aubry A, Amiot M, Pellat-Deceunynck C. A simple flow cytometry-based barcode for routine authentication of multiple myeloma and mantle cell lymphoma cell lines. Cytometry A. 2015 Apr;87(4):285-8.-(MNT Team: INSERM UMR 892/CNRS 6299 team 10 – Nantes)
  • Lézot F, Chesneau J, Navet B, Gobin B, Amiaud J, Choi Y, Yagita H, Castaneda B, Berdal A, Mueller CG, Rédini F, Heymann D. Skeletal consequences of RANKL-blocking antibody (IK22-5) injections during growth: mouse strain disparities and synergic effect with Zoledronic acid. Bone. 2015 Apr;73:51-9. - (MNT team: INSERM UMR 957 - Nantes)
  • Mazuryk O, Suzenet F, Kieda C, Brindell M. The biological effect of the nitroimidazole derivative of a polypyridyl ruthenium complex on cancer and endothelial cells. Metallomics. 2015 Mar 11;7(3):553-66. - (MNT Team: CNRS UPR4301 - CBM - Orléans)
  • Guihard P, Boutet MA, Brounais-Le Royer B, Gamblin AL, Amiaud J, Renaud A, Berreur M, Rédini F, Heymann D, Layrolle P, Blanchard F. Oncostatin M, an inflammatory cytokine produced by macrophages, supports intramembranous bone healing in a mouse model of tibia injury. Am J Pathol. 2015 Mar;185(3):765-75. - (MNT team: INSERM UMR 957 - Nantes)
  • Gobin B, Huin MB, Lamoureux F, Ory B, Charrier C, Lanel R, Battaglia S, Redini F, Lezot F, Blanchard F, Heymann D. BYL719, a new α-specific PI3K inhibitor: single administration and in combination with conventional chemotherapy for the treatment of osteosarcoma. Int J Cancer. 2015 Feb 15;136(4):784-96. - (MNT team: INSERM UMR 957 - Nantes)
  • Ginisty A, Gély-Pernot A, Abaamrane L, Morel F, Arnault P, Coronas V#, Benzakour O#. Evidence for a subventricular zone neural stem cell phagocytic activity stimulated by the vitamin k-dependent factor protein s. Stem Cells. 2015 Feb;33(2):515-25. #co-last author - (MNT team: CNRS ERL 7368 - Poitiers) - Press
  • Cobret L, De Tauzia ML, Ferent J, Traiffort E, Hénaoui I, Godin F, Kellenberger E, Rognan D, Pantel J, Bénédetti H, Morisset-Lopez S. Targeting the cis-dimerization of LINGO-1 with low MW compounds affects its downstream signalling. Br J Pharmacol. 2015 Feb;172(3):841-56.- (MNT Team: CNRS UPR4301 - CBM - Orléans)
  • Laffleur B, Duchez S, Tarte K, Denis-Lagache N, Péron S, Carrion C, Denizot Y, Cogné M. Self-Restrained B Cells Arise following Membrane IgE Expression. Cell Rep. 2015 Feb 12. pii: S2211-1247(15)00048-0. (MNT Team: INSERM UMR 917 – Rennes)
  • Kassambara A, Rème T, Jourdan M, Fest T, Hose D, Tarte K, Klein B. GenomicScape: an easy-to-use web tool for gene expression data analysis. Application to investigate the molecular events in the differentiation of B cells into plasma cells. PLoS Comput Biol. 2015 Jan 29;11(1):e1004077. (MNT Team: INSERM UMR 917 – Rennes)
  • Bigot N, Guérillon C, Loisel S, Bertheuil N, Sensebé L, Tarte K, Pedeux R. ING1b negatively regulates HIF1α protein levels in adipose-derived stromal cells by a SUMOylation-dependent mechanism. Cell Death Dis. 2015 Jan 22;6:e1612. (MNT Team: INSERM UMR 917 – Rennes)
  • Misiak J, Tarte K, Amé-Thomas P. Flow cytometric detection and isolation of human tonsil or lymph node T follicular helper cells. Methods Mol Biol. 2015;1291:163-73. (MNT Team: INSERM UMR 917 – Rennes)
  • Collet G, El Hafny-Rahbi B, Nadim M, Tejchman A, Klimkiewicz K, Kieda C. Hypoxia-shaped vascular niche for cancer stem cells. Int J Cancer. Contemp Oncol (Pozn). 2015;19(1A):A39-43. (MNT Team: CNRS UPR4301 - CBM - Orléans)
  • Guiho R, Biteau K, Heymann D, Redini F. TRAIL-based therapy in pediatric bone tumors: how to overcome resistance. Future Oncol. 2015;11(3):535-42. - (MNT team: INSERM UMR 957 - Nantes)
  • Segaliny AI, Tellez-Gabriel M, Heymann MF, Heymann D. Receptor tyrosine kinases: characterisation, mechanism of action and therapeutic interests for bone cancers. J Bone Oncol. 2015 Jan 23;4(1):1-12. - (MNT team: INSERM UMR 957 - Nantes)
  • Nadim M, Hassanaly S,Dubannet L and Grillon C. Physioxia and MicroRNAs As Key Factors in the Skin Microenvironment. IFSCC Magazine 18(1): 35-43. - (MNT Team: CNRS UPR4301 - CBM - Orléans)
  • Avril P, Le Nail L-R ,Brennan MA , Rosset P, De Pinieux G, Layrolle P, Heymann D, , Perrot P, Trichet V. Mesenchymal stem cells enhance proliferation but do not change quiescent state of osteosarcoma cells: different implication before and after tumor resection. Journal of Bone Oncology doi:10.1016/j.jbo.2015.11.002. - (MNT team: INSERM UMR 957 - Nantes)
  • Avril P, Ridel P, Heymann MF, De Pinieux G, Rédini F, Blanchard F, Heymann D, Trichet V, Perrot P. Opposite effects of soluble factors secreted by adipose tissue on proliferating and quiescent osteosarcoma cells. Plastic and reconstructive Surgery, in press PRS-D-15-00778. - (MNT team: INSERM UMR 957 - Nantes)
  • Pellat-Deceunynck C, Defrance T. The origin of the plasma-cell heterogeneity. Front Immunol. 2015 Jan 23;6:5.-(MNT Team: INSERM UMR 892/CNRS 6299 team 10 – Nantes)
  • Gomez-Bougie P, Halliez M, Maïga S, Godon C, Kervoëlen C, Pellat-Deceunynck C, Moreau P, Amiot M. Curcumin induces cell death of the main molecular myeloma subtypes, particularly the poor prognosis subgroups. Cancer Biol Ther. 2015;16(1):60-5.-(MNT Team: INSERM UMR 892/CNRS 6299 team 10 – Nantes)