CRCINA - INSERM UMR1232
Department "Oncogenesis and new concepts in oncology (ONCO)"
Team 14: Endothelium radiobiology and targeting
Team description
Keywords: Radiotherapy, vascular response, sphingolipid, mathematical modeling
The Team 14 of the Cancer Research Center Nantes-Angers studies the involvement of endothelial cells during the tumor response or the normal tissue toxicity. This research on fundamental and preclinical radiobiology will be integrated into a multiparametric mathematical model linking the induction of our molecular actors and the radioinduced anti-tumor response. The aim is to understand new pharmacological or immunological strategies modulating the response to radiotherapy treatments.
Expertises / technical competence
Expertises
Radiobiology/ Radiotherapy
Cell signaling
Lipid biochemistry
Technical competence
Lipidomic, phenomique
Signal transduction
Antibody engineering
Stereoxatic radiotherapy
Collaborations
Grand Ouest
O. Acosta, LTSI, Inserm U1099, Rennes
National
S. Rivera, Service de Radiothérapie, IGR, Paris
JL Perfettini, Inserm UMR 1230, IGR Paris
L. Sabatier, LRO Team - Institut de biologie François Jacob – CEA, Fontenay aux Roses
International
B. Sorensen, Aarhus University, Aarhus, Denmark
E. Hadchiti, Univ. Libanaise, Hadhat, Liban
R. Kolesnick, MSKCC, NY, USA
Place - Find us
Institut de Recherche en Santé de l'Université de Nantes
8 quai Moncousu